The Importance of Cabergoline....or at least having it on hand.
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01dragonslayer
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Good ya hear. Thats how it rolls here at HCU....we help each other out.
01dragonslayer
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Iv'e ran NPP along with tren and no issues.
01dragonslayer
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You are right my friend....more is not always better in this field. Many young cyclers don't understand that you want to use the least amount of hormone you can to see the results you want. Starting lower doses and slowing increasing your dose is always more beneficial than running a high dose from the get go just because "he said so". Always see how your body may react to a hormone before increasing the dose or possibly discontinuing altogether.
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muscle1031
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I've ran deca up to 800mg and never needed caber because I've always kept my estrogen in check around 11-25. I've ran it at 800mg on trt and on 750mg of test. When I ran on trt it seems to be much more effective and clean. And obviously much easier to control estrogen also. My buddy who knows a thing or 2 posted this and I'll share.
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We all know the same old spiel that we should use .5mg or .25mg dostinex twice a week throughout any cycle that utilizes compounds that can increase PRL such as Nor19s, IGF1, GH, GH secretagogues etc.., but is this truly necessary ? lets find out just how strong caber really is:
"Cabergoline induced a marked fall in serum PRL level, starting within 3 h and continuing for 7 days after administering 0.3 mg, and for 14 days after 0.6 mg. The mean maximal decrease was 49% after 0.3 mg and 63% after 0.6 mg and occurred after 24 h in both cases. Serum GH levels did not change after 0.3 mg of cabergoline, but decreased significantly from 3 h to 3 days after 0.6 mg of the compound with a mean maximal decrease of 42% after 24 h. Once a week repeated administration of 0.3-0.6 mg of cabergoline was carried out in six patients, five of whom had completed the acute study; a normalization of serum GH and insulin-like growth factor I (IGF-I) levels occurred in three patients, one of whom had very high pretreatment values. In three poorly or nonresponsive patients, a better response, as assessed by both GH and IGF-I levels, was induced by increasing the dose up to 0.6 mg twice or 0.4 mg three times a week; in one case this was associated with marked tumour shrinkage. Sustained normalization of PRL levels was achieved in all cases. These data indicate that a single dose of 0.6 mg of cabergoline inhibits GH as well as PRL secretion in dopamine-responsive acromegalic patients and suggests that doses of 0.3-0.6 mg once to three times a week may prove suitable for treatment of this condition."
https://www.ncbi.nlm.nih.gov/pubmed/2908102
so what we can take from this is that Cabergoline is extremely potent and that after administering 1 single dose its user can possibly expect to see their nadir mean maximal decrease to be 49%+/- after 0.3 mg and 63%+/- after 0.6 mg and occurred after 24 h in both cases... Keep in mind this compound was developed to treat hyperprolactinemia, acromegaly, and pituitary tumors called prolactinoma and with PRL ranges sometimes into the hundreds ng/ml. . So the next time anyone pulls a PRL test and notices a slight increase be aware that a single dose @ 0.3mg caber could possibly reduce the nadir mean by half +/-, so sparing use is advised and only if needed. Otherwise zeroing PRL is extremely likely with ongoing prolonged usage and could exhibit side effects such as unexplained headaches, visual impairment, reduced sex drive or fertility problems, erectile dysfunction, abnormal lack of body and facial hair. Good comparison would be equivalent to crashing Estradiol, which should also be avoided.
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=========
We all know the same old spiel that we should use .5mg or .25mg dostinex twice a week throughout any cycle that utilizes compounds that can increase PRL such as Nor19s, IGF1, GH, GH secretagogues etc.., but is this truly necessary ? lets find out just how strong caber really is:
"Cabergoline induced a marked fall in serum PRL level, starting within 3 h and continuing for 7 days after administering 0.3 mg, and for 14 days after 0.6 mg. The mean maximal decrease was 49% after 0.3 mg and 63% after 0.6 mg and occurred after 24 h in both cases. Serum GH levels did not change after 0.3 mg of cabergoline, but decreased significantly from 3 h to 3 days after 0.6 mg of the compound with a mean maximal decrease of 42% after 24 h. Once a week repeated administration of 0.3-0.6 mg of cabergoline was carried out in six patients, five of whom had completed the acute study; a normalization of serum GH and insulin-like growth factor I (IGF-I) levels occurred in three patients, one of whom had very high pretreatment values. In three poorly or nonresponsive patients, a better response, as assessed by both GH and IGF-I levels, was induced by increasing the dose up to 0.6 mg twice or 0.4 mg three times a week; in one case this was associated with marked tumour shrinkage. Sustained normalization of PRL levels was achieved in all cases. These data indicate that a single dose of 0.6 mg of cabergoline inhibits GH as well as PRL secretion in dopamine-responsive acromegalic patients and suggests that doses of 0.3-0.6 mg once to three times a week may prove suitable for treatment of this condition."
https://www.ncbi.nlm.nih.gov/pubmed/2908102
so what we can take from this is that Cabergoline is extremely potent and that after administering 1 single dose its user can possibly expect to see their nadir mean maximal decrease to be 49%+/- after 0.3 mg and 63%+/- after 0.6 mg and occurred after 24 h in both cases... Keep in mind this compound was developed to treat hyperprolactinemia, acromegaly, and pituitary tumors called prolactinoma and with PRL ranges sometimes into the hundreds ng/ml. . So the next time anyone pulls a PRL test and notices a slight increase be aware that a single dose @ 0.3mg caber could possibly reduce the nadir mean by half +/-, so sparing use is advised and only if needed. Otherwise zeroing PRL is extremely likely with ongoing prolonged usage and could exhibit side effects such as unexplained headaches, visual impairment, reduced sex drive or fertility problems, erectile dysfunction, abnormal lack of body and facial hair. Good comparison would be equivalent to crashing Estradiol, which should also be avoided.
Sent from my SAMSUNG-SM-N920A using Tapatalk
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