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How Should We Choose Between SS-31 and MOTS-c?

AASraw

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Oct 22, 2017
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In the fields of anti-aging, metabolic enhancement, and cellular protection, SS-31 and MOTS-c are two rising stars you should know about.

Let’s break them down: Both SS-31 and MOTS-c are gaining significant traction in anti-aging science, metabolic health, and mitochondrial research. Here’s a side-by-side comparison of their characteristics and potential applications:

MOTS-c
1.A naturally occurring peptide encoded by mitochondrial DNA (13 amino acids)
2.Activates AMPK pathway, improves insulin sensitivity
3.Regulates fat metabolism, supports endurance and energy balance
4.Commonly studied in metabolic disorders, obesity, and aging research
SS-31
1.A synthetic tetrapeptide designed to target mitochondria directly
2.Protects mitochondrial membrane and reduces oxidative stress
3.Supports cellular health in heart, brain, and muscle tissues
4.Often researched for neurodegeneration, cardiovascular issues, and mitochondrial dysfunction

So How to Choose?

Studying metabolism and energy balance? → MOTS-c may be your go-to.
Focusing on mitochondrial protection and oxidative damage? → SS-31 is often the peptide of choice.
 
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