Rambo - Peptide and SARM Q&A

[RamboStallone]

Hey guys, this thread will be for answering questions related to peptides, SARMs, chems, etc. Since I get the same questions frequently I decided we can share the questions and answers with everyone to further all of our knowledge on these relatively new to the scene compounds. Sometimes it's hard for me to relay lots of information unless I get asked, so please PICK MY BRAIN!

Thanks and enjoy!

 

[Gone]

This is awesome, as i know you are the peptide GURU,
i`ll start this off
Years ago i tried, S1...a SARM when it first came out....main thing i did notice was it gave me blurry vision. i never used it since, was it that particular sarm, have sides changed?

 

[Pipelinesteve4]

Compare sr9009 to gw50 for me.coffee==

 

[RamboStallone]

This is awesome, as i know you are the peptide GURU,
i`ll start this off
Years ago i tried, S1...a SARM when it first came out....main thing i did notice was it gave me blurry vision. i never used it since, was it that particular sarm, have sides changed?

You're thinking of S4. Yes that particular SARM messes with the eye's. The other SARMs don't have this issue. I'll be perfectly honest, if you are using AAS these SARMs are going to be one big disappointment. However, MK677 which is mislabeled as a SARM is actually a GH secretagogue which can benefit everyone. GW is another that is not really a SARM but a PPAR-DELTA agonist which can help lipids, endurance, and fat loss. SR is similar to GW. RAD140 is a SARM that was shown to increase the effects of testosterone propionate and protect the prostate, this is a newer one that can be used to "amplify" your AAS cycle. I ran it once and the anxiety caused me to stop, way worse then EQ or tren anxiety. Could have been the RAD "amplifying" the other gear I was on (including tren iirc).

RAD140 study below,

"RAD140 had a greater anabolic effect than testosterone, but fewer androgenic side effects. When the researchers combined RAD140 and testosterone, RAD140 reinforced the anabolic effects of testosterone, but reduced the androgenic side effects of testosterone on the prostate. That might mean that RAD140 can make testosterone cycles more effective and safer."

http://www.ergo-log.com/even-just-a-few-mg-of-rad140-has-anabolic-effect.html

 

[RamboStallone]

Compare sr9009 to gw50 for me.coffee==

I don't have too much personal experience with these. I'm using GW for the first time now and I am definitely noticing an endurance increase. I'm bulking so can't tell any fat loss. They are both very similar in effects, except it seems like guys who like GW, love SR. With these particular drugs, people either get the effects and love it or others notice barely anything at all. I'm waiting for my next bloodwork to see what my lipids look like. So while SR seems stronger it's drawbacks are it's more expensive and it needs to be dosed multiple times a day. Most guys preferred 3-4x a day to see real good effects.

 

[green22]

How is your TB500, do you have much feed back or have u needed to use yourself. I just need to save a lil more cash to make a decent purchase. Ive used in the past and feel it does help but lab I have used is way more pricey. Thanks

 

[Pipelinesteve4]

How is your TB500, do you have much feed back or have u needed to use yourself. I just need to save a lil more cash to make a decent purchase. Ive used in the past and feel it does help but lab I have used is way more pricey. Thanks

Rambo is top end. He isn't greedy and passes his savings along to us. He is as solid as they come. You don't ever have to worry when dealing with him. I have used alot of different stuff of his (not tb500) and all has been excellent

 

[drealdeal]

Great idea! And what an amazing way to give back! Thanks Rambo!

Sent from my N9132 using Tapatalk

 

[green22]

Rambo is top end. He isn't greedy and passes his savings along to us. He is as solid as they come. You don't ever have to worry when dealing with him. I have used alot of different stuff of his (not tb500) and all has been excellent

Thanks PipeLine, Im gonna give him a shot!!!!!!

 

[Hardcore-Cody]

My question is about Ghrp 6...Research has found that the consumption of carbohydrates around the administration window of GH secretagogues significantly blunts the GH release....What is the window for Ghrp 6?

 

[RamboStallone]

Great idea! And what an amazing way to give back! Thanks Rambo!

Sent from my N9132 using Tapatalk

Thanks brother.

 

[RamboStallone]

Thanks PipeLine, Im gonna give him a shot!!!!!!

Like pipeline said I am passing along the savings brother. Just purchase small to try out if you're concerned before making a big order. I personally haven't given TB500 a solid run, even though I do have some aches the GH secretagogues/peptides seem to help this while I am on. I have been thinking of adding TB500 to my stack to see if it will heal my knees and help any tendinitis but I haven't done it yet. For now the the rise in GH has been enough to help and keep me progressing in weight.

 

[Pipelinesteve4]

Like pipeline said I am passing along the savings brother. Just purchase small to try out if you're concerned before making a big order. I personally haven't given TB500 a solid run, even though I do have some aches the GH secretagogues/peptides seem to help this while I am on. I have been thinking of adding TB500 to my stack to see if it will heal my knees and help any tendinitis but I haven't done it yet. For now the the rise in GH has been enough to help and keep me progressing in weight.

I recall reading something about bpc157 combined with hgh have a super synergistic effect because of the bpc increasing receptor attachment or something like that. Wish I could find it but I believe it was lost when dats forum was ended (extremely unfortunate that all that information was lost senselessly)

 

[RamboStallone]

My question is about Ghrp 6...Research has found that the consumption of carbohydrates around the administration window of GH secretagogues significantly blunts the GH release....What is the window for Ghrp 6?

This theory has been disproven and there is no research that this occurred in humans that I have seen.

What I can say is, from real world experience and testing that was done by an anti-aging doctor on another board. Carbs and fats did not blunt or affect ghrp2 and mod. The serum score still came back high. He also found that 100/100mcgs of ghrp2 and mod gave similar gh elevation to 500/250mcgs. Meaning, it's more important with the ghrp/ghrh combos to dose them multiple times a day then it is to dose them high. But we have seen this in the studies as well on other gh secretagogues, the GH doesn't significantly rise with higher doses but the IGF-I does. So if you are after the higher IGF-I levels, it makes perfect sense to take advantage of higher doses.

All in all, us bbers are literally on a full stomach all the time. If these PEDs are blunted by food, none of us would see any effects. No worries with dosing and eating interaction in my opinion. The body works in steps with multiple mechanisms at play, much different then a lab environment.

 

[Hardcore-Cody]

You are THE MAN!!

 

[Hardcore-Cody]

We are lucky to have your knowledge here bro!

 

[RamboStallone]

I recall reading something about bpc157 combined with hgh have a super synergistic effect because of the bpc increasing receptor attachment or something like that. Wish I could find it but I believe it was lost when dats forum was ended (extremely unfortunate that all that information was lost senselessly)

Yes, see below.


Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts.

Chang CH1, Tsai WC2, Hsu YH3, Pang JH4.

Abstract
BPC 157, a pentadecapeptide derived from human gastric juice, has been demonstrated to promote the healing of different tissues, including skin, muscle, bone, ligament and tendon in many animal studies. However, the underlying mechanism has not been fully clarified. The present study aimed to explore the effect of BPC 157 on tendon fibroblasts isolated from Achilles tendon of male Sprague-Dawley rat. From the result of cDNA microarray analysis, growth hormone receptor was revealed as one of the most abundantly up-regulated genes in tendon fibroblasts by BPC 157. BPC 157 dose- and time-dependently increased the expression of growth hormone receptor in tendon fibroblasts at both the mRNA and protein levels as measured by RT/real-time PCR and Western blot, respectively. The addition of growth hormone to BPC 157-treated tendon fibroblasts dose- and time-dependently increased the cell proliferation as determined by MTT assay and PCNA expression by RT/real-time PCR. Janus kinase 2, the downstream signal pathway of growth hormone receptor, was activated time-dependently by stimulating the BPC 157-treated tendon fibroblasts with growth hormone. In conclusion, the BPC 157-induced increase of growth hormone receptor in tendon fibroblasts may potentiate the proliferation-promoting effect of growth hormone and contribute to the healing of tendon.

 

[Hardcore-Cody]

But why I asked is because I try to wait as long as I can after dosing, but I go semi hypo after about 10-15 minutes and have to stuff my face,lol, so I didnt want to be defeating the purpose,, thanks again for the quick response!

 

[RamboStallone]

But why I asked is because I try to wait as long as I can after dosing, but I go semi hypo after about 10-15 minutes and have to stuff my face,lol, so I didnt want to be defeating the purpose,, thanks again for the quick response!

No problem bud, thanks for the kind words. Exactly bro, you start going hypo so obviously eating is not a problem, your body is telling you it needs the glucose. In none of the studies I have read was food ever mentioned as a problem. Ghrp6 and MK677 have similar structures, basically on paper MK677 is a long acting oral Ghrp6 on steroids (no pun intended ) so should we fast all day on MK677, lol I don't think so.

 

[RamboStallone]

To add, these gh secretagogues work through ghrelin to release HGH, and ghrelin also happens to increase hunger so what does that tell us? Food shouldn't be a problem.