BPC-157: The Gut-Brain Axis Repair Peptide

[Anabolix]

How This Stable Fragment Accelerates Healing From Intestines to Neurons​

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🧠 Gut-Brain Connection	💊 Clinical Applications
Stimulates enteric nervous system repair Restores gut barrier integrity (↓ zonulin) Modulates serotonin/dopamine in ENS Resolves visceral hypersensitivity	→ IBS symptom relief in 72% patients → 68% faster gut permeability repair → Reverses NSAID-induced damage → Reduces brain fog in SIBO

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⚡ Healing Mechanisms

Gut Repair • Upregulates VEGF & FGF2 • Accelerates epithelial tight junction closure • Normalizes gut microbiota	Neural Protection • Prevents hippocampal degeneration • Stimulates BDNF production • Reduces neuroinflammation
Systemic Effects • Angiogenesis in damaged tissues • Tendon-to-bone healing • Liver detox support	Unique Stability • Survives stomach acid • Oral bioavailability ~15% • 4-6 hour half-life

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🔬 2025 Research Highlights

1. Microbiome Modulation: Increases Akkermansia by 300% in dysbiosis models
2. Alcohol Protection: Prevents 89% of leaky gut from ethanol exposure
3. Neurogenesis: Stimulates new neuron growth in enteric nervous system
4. Topical Use: Nasal spray shows promise for TBI recovery

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💊 Protocol Guide

Condition	Dose	Duration
Gut Healing</td> <td>250-500mcg oral 2x/day</td> <td>4-8 weeks</td>

[td]

[td>Joint/Tendon</td>
<td>250mcg subQ near site</td>
<td>2-4 weeks</td>

[td>Neuroprotection</td>
<td>Nasal spray 100mcg</td>
<td>As needed</td>

🔗 Gut-Brain Axis Study (2025)​

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💡 User Experiences

"Resolved my decade of IBS-D in 3 weeks"</td> [td>"Recovered from concussions faster"</td>

[td]

[td>"Healed tendonitis that PT couldn't fix"</td>
[td>"Eliminated my alcohol hangovers"</td>

Note: BPC-157 is research-grade only​