How to extrapolate doses from animals to humans

invalid@example.com (01dragonslayer), 01dragonslayer
Fri, 20 Mar 2026 13:22:23 +0000
GENERAL DISCUSSION

By Marco D. Angelo
A direct extrapolation of the effects observed in a clinical trial in rodents or other animals to one in humans cannot be used based solely on body weight due to differences in metabolism of the different species.

An example of this would be to calculate human equivalent...